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Antibodies

GRK1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA909936-50UL
100 ul
£334.00
CSB-PA909936-100UL
About this Product
SKU:
CSB-PA909936
Additional Names:
EC=2.7.11.14 antibody; G protein-coupled receptor kinase 1 antibody; GPRK1 antibody; Grk1 antibody; Rhodopsin kinase antibody; RHOK antibody; RK antibody; RK_HUMAN antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human GRK1
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA909936(GRK1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA909936(GRK1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)