KCNJ11 Antibody
Product Sizes
50 ul
£186.00
CSB-PA907180-50UL
100 ul
£334.00
CSB-PA907180-100UL
About this Product
- SKU:
- CSB-PA907180
- Additional Names:
- KCNJ11 antibody; ATP-sensitive inward rectifier potassium channel 11 antibody; IKATP antibody; Inward rectifier K(+) channel Kir6.2 antibody; Potassium channel antibody; inwardly rectifying subfamily J member 11 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human KCNJ11
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:KCNJ11-Antibody-11101302.html
