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Antibodies

DAB1 (Ab-232) Antibody

Product Sizes
100 ul
£332.00
CSB-PA907168-100UL
About this Product
SKU:
CSB-PA907168
Additional Names:
Dab 1 antibody; Dab reelin signal transducer 1 antibody; Dab; reelin signal transducer; homolog 1 (Drosophila) antibody; Dab1 antibody; DAB1_HUMAN antibody; Disabled homolog 1 antibody; Disabled homolog 1 Drosophila antibody; Scm antibody; Scr antibody; Scrambler antibody; Yot antibody; Yotari antibody
Application:
ELISA, Immunohistochemistry
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. Kelian Chen, et,al. (2003) J. Cell Sci ; 117: 4527 - 4536. Vera Strasser, et,al. (2004) Mol. Cell. Biol ; 24: 1378 - 1386. Izhar Ben-Shlomo, et,al. (2003) Sci. STKE ; 2003: 9. H. M. Kim, et,al. (2002) PNAS ; 99: 4020.
Host:
Rabbit
Immunogen:
Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody