NUMBL Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA897595LC01HU-50UG
100 ug
£334.00
CSB-PA897595LC01HU-100UG
About this Product
- SKU:
- CSB-PA897595LC01HU
- Additional Names:
- CAG 3A antibody; CAG3A antibody; CTG 3a antibody; CTG3a antibody; NBL antibody; NUMB Drosophilia Homolog Like antibody; Numb homolog (Drosophila) like antibody; Numb homolog like antibody; Numb like protein antibody; NUMB R antibody; Numb-like protein antibody; Numb-R antibody; Numb-related gene antibody; Numb-related protein antibody; NUMBL antibody; NUMBL_HUMAN antibody; NUMBLIKE antibody; NUMBR antibody; TNRC 23 antibody; TNRC23 antibody; Trinucleotide repeat-containing gene 23 antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Numb-like protein (447-576AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NUMBL-Antibody-FITC-conjugated-12785020.html
