L3MBTL1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA897111ESR2HU-50UL
100 ul
£334.00
CSB-PA897111ESR2HU-100UL
About this Product
- SKU:
- CSB-PA897111ESR2HU
- Additional Names:
- dJ138B7.3 antibody; H-L(3)MBT antibody; H-l(3)mbt protein antibody; KIAA0681 antibody; L(3)mbt protein homolog antibody; L(3)mbt-like antibody; L3MBT antibody; L3MBTL antibody; L3MBTL1 antibody; Lethal (3) malignant brain tumor l(3 antibody; Lethal(3)malignant brain tumor-like protein 1 antibody; LMBL1_HUMAN antibody; RGD1307316 antibody; ZC2HC3 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys-860'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Lethal(3)malignant brain tumor-like protein 1 protein (513-752AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:L3MBTL1-Antibody-11089986.html
