DMRT1 Antibody, HRP conjugated
Product Sizes
50 ug
£186.00
CSB-PA896914LB01HU-50UG
100 ug
£334.00
CSB-PA896914LB01HU-100UG
About this Product
- SKU:
- CSB-PA896914LB01HU
- Additional Names:
- CT154 antibody; DM domain expressed in testis 1 antibody; DM domain expressed in testis protein 1 antibody; DM domain gene expressed in testis antibody; DMRT 1 antibody; dmrt1 antibody; DMRT1_HUMAN antibody; DMT 1 antibody; DMT1 antibody; Doublesex and mab 3 related transcription factor 1 antibody; Doublesex- and mab-3-related transcription factor 1 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Extra Details:
- Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DMRT1-AntibodyHRP-conjugated-12549494.html
