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Antibodies

FBXO2 Antibody

Product Sizes
50 ul
£186.00
CSB-PA892326ESR1HU-50UL
100 ul
£334.00
CSB-PA892326ESR1HU-100UL
About this Product
SKU:
CSB-PA892326ESR1HU
Additional Names:
F box gene 1 antibody; F box only protein 2 antibody; F box protein 2 antibody; F box protein only 2 antibody; F-box only protein 2 antibody; FBG 1 antibody; FBG1 antibody; Fbs 1 antibody; Fbs1 antibody; Fbs2 antibody; FBX 2 antibody; FBX2 antibody; FBX2_HUMAN antibody; FBXO 2 antibody; FBXO2 antibody; Neural F box protein NFB42 antibody; Neural F-box protein; 42-KD; rat; homolog of antibody; NFB 42 antibody; NFB42 antibody; OCP1 antibody; organ of Corti protein 1 antibody; Prpl4 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human F-box only protein 2 protein (1-296AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody