POLI Antibody
Product Sizes
50 ug
£186.00
CSB-PA892157LA01HU-50UG
100 ug
£334.00
CSB-PA892157LA01HU-100UG
About this Product
- SKU:
- CSB-PA892157LA01HU
- Additional Names:
- DNA polymerase iota antibody; Eta 2 antibody; Eta2 antibody; POLI antibody; POLI_HUMAN antibody; Polymerase (DNA directed) iota antibody; RAD 30B antibody; RAD30 homolog B antibody; RAD30, S. cerevisiae, homolog of antibody; RAD30B antibody; RAD3OB antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA polymerase iota protein (458-711AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:POLI-Antibody-12555636.html
