TPX2 Antibody
Product Sizes
50 ug
£186.00
CSB-PA892151LA01HU-50UG
100 ug
£334.00
CSB-PA892151LA01HU-100UG
About this Product
- SKU:
- CSB-PA892151LA01HU
- Additional Names:
- C20ORF1 antibody; C20orf2 antibody; Chromosome 20 Open Reading Frame 1 antibody; Differentially expressed in cancerous and non-cancerous lung cells 2 antibody; Differentially expressed in cancerous and noncancerous lung cells 2 antibody; Differentially expressed in lung cells 2 antibody; Differentially expressed in lung cells antibody; DIL 2 antibody; DIL-2 antibody; DIL2 antibody; FLS353 antibody; GD:C20orf1 antibody; HCA 519 antibody; HCA519 antibody; HCTP 4 antibody; HCTP4 antibody; Hepatocellular carcinoma associated antigen 519 antibody; Hepatocellular carcinoma-associated antigen 519 antibody; p100 antibody; Preferentially expressed in colorectal cancer antibody; Protein fls353 antibody; REPP 86 antibody; repp86 antibody; Restricted expression proliferation associated protein 100 antibody; Restricted expression proliferation-associated protein 100 antibody; Targeting protein for Xklp2 antibody; TPX 2 antibody; TPX2 antibody; TPX2 microtubule associated homolog antibody; TPX2 microtubule associated protein homolog antibody; TPX2 microtubule nucleation factor antibody; TPX2_HUMAN antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Targeting protein for Xklp2 protein (160-320AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:TPX2-Antibody-12782425.html
