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Antibodies

TNFSF18 Antibody

Product Sizes
50 ul
£186.00
CSB-PA891791ESR1HU-50UL
100 ul
£334.00
CSB-PA891791ESR1HU-100UL
About this Product
SKU:
CSB-PA891791ESR1HU
Additional Names:
Activation inducible TNF related ligand antibody; Activation-inducible TNF-related ligand antibody; AITR ligand antibody; AITRL antibody; GITR ligand antibody; GITRL antibody; Glucocorticoid induced TNF related ligand antibody; Glucocorticoid induced TNFR related protein ligand antibody; Glucocorticoid-induced TNF-related ligand antibody; hGITRL antibody; MGC138237 antibody; TL6 antibody; TNF18_HUMAN antibody; TNFSF18 antibody; TNLG2A antibody; Tumor necrosis factor (ligand) superfamily member 18 antibody; Tumor necrosis factor ligand 2A antibody; Tumor necrosis factor ligand superfamily member 18 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
Host:
Rabbit
Immunogen:
Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (72-199AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody