Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

FZD10 Antibody, HRP conjugated

Product Sizes
50 ug
£186.00
CSB-PA891782LB01HU-50UG
100 ug
£334.00
CSB-PA891782LB01HU-100UG
About this Product
SKU:
CSB-PA891782LB01HU
Additional Names:
CD 350 antibody; CD 350 antigen antibody; CD350 antibody; Frizzled (Drosophila) homolog 10 antibody; Frizzled-10 antibody; FZ 10 antibody; Fz-10 antibody; FZ10 antibody; FZD 10 antibody; FZD10 antibody; FZD10_HUMAN antibody; FzE 7 antibody; FzE7 antibody; hFz 10 antibody; hFz10 antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Conjugate:
HRP
Extra Details:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Host:
Rabbit
Immunogen:
Recombinant Human Frizzled-10 protein (125-225AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody