DROSHA Antibody
Product Sizes
50 ul
£186.00
CSB-PA889096LA01HU-50UL
100 ul
£334.00
CSB-PA889096LA01HU-100UL
About this Product
- SKU:
- CSB-PA889096LA01HU
- Additional Names:
- DROSHA antibody; Drosha double stranded RNA specific endoribonuclease antibody; Drosha ribonuclease type III antibody; Etohi2 antibody; HSA242976 antibody; Nuclear RNase III Drosha antibody; p241 antibody; Protein Drosha antibody; Putative protein p241 which interacts with transcription factor Sp1 antibody; Putative ribonuclease III antibody; RANSE3L antibody; Ribonuclease 3 antibody; Ribonuclease III antibody; Ribonuclease III nuclear antibody; Ribonuclease type III nuclear antibody; RibonucleaseIII antibody; RN 3 antibody; RN3 antibody; RNase 3 antibody; RNase III antibody; RNase3 antibody; RNASE3L antibody; RNaseIII antibody; RNASEN antibody; RNC_HUMAN antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Ribonuclease 3 protein (1-100AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DROSHA-Antibody-12927797.html
