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Antibodies

MBNL1 Antibody, HRP conjugated

Product Sizes
50 ug
£186.00
CSB-PA889088LB01HU-50UG
100 ug
£334.00
CSB-PA889088LB01HU-100UG
About this Product
SKU:
CSB-PA889088LB01HU
Additional Names:
EXP antibody; EXP35 antibody; EXP40 antibody; EXP42 antibody; KIAA0428 antibody; MBNL antibody; MBNL protein antibody; MBNL1 antibody; MBNL1_HUMAN antibody; Muscleblind 41kD isoform antibody; Muscleblind like antibody; Muscleblind like protein 1 antibody; Muscleblind like splicing regulator 1 antibody; Muscleblind-like protein 1 antibody; Triplet expansion RNA binding protein antibody; Triplet-expansion RNA-binding protein antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
HRP
Extra Details:
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
Host:
Rabbit
Immunogen:
Recombinant Human Muscleblind-like protein 1 protein (1-382AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody