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Antibodies

ARL6 Antibody

Product Sizes
50 ul
£186.00
CSB-PA887945ESR1HU-50UL
100 ul
£334.00
CSB-PA887945ESR1HU-100UL
About this Product
SKU:
CSB-PA887945ESR1HU
Additional Names:
ADP ribosylation factor like 6 antibody; ADP ribosylation factor like protein 6 antibody; ADP-ribosylation factor-like protein 6 antibody; Arl6 antibody; ARL6_HUMAN antibody; Bardet Biedl syndrome 3 protein antibody; Bardet-Biedl syndrome 3 protein antibody; BBS3 antibody; MGC32934 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human ADP-ribosylation factor-like protein 6 protein (1-186AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody