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Antibodies

QTRT1 Antibody, HRP conjugated

Product Sizes
50 ug
£186.00
CSB-PA887150LB01HU-50UG
100 ug
£334.00
CSB-PA887150LB01HU-100UG
About this Product
SKU:
CSB-PA887150LB01HU
Additional Names:
FP3235 antibody; Guanine insertion enzyme antibody; qtrt1 antibody; Queuine tRNA ribosyltransferase 1 antibody; Queuine tRNA ribosyltransferase antibody; Queuine tRNA-ribosyltransferase antibody; TGT antibody; TGT, 43 KD subunit antibody; TGT, catalytic subunit antibody; TGT_HUMAN antibody; TGUT antibody; tRNA guanine transglycosylase antibody; tRNA-guanine transglycosylase antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
HRP
Extra Details:
Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody