QTRT1 Antibody
Product Sizes
50 ug
£186.00
CSB-PA887150LA01HU-50UG
100 ug
£334.00
CSB-PA887150LA01HU-100UG
About this Product
- SKU:
- CSB-PA887150LA01HU
- Additional Names:
- FP3235 antibody; Guanine insertion enzyme antibody; qtrt1 antibody; Queuine tRNA ribosyltransferase 1 antibody; Queuine tRNA ribosyltransferase antibody; Queuine tRNA-ribosyltransferase antibody; TGT antibody; TGT, 43 KD subunit antibody; TGT, catalytic subunit antibody; TGT_HUMAN antibody; TGUT antibody; tRNA guanine transglycosylase antibody; tRNA-guanine transglycosylase antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:QTRT1-Antibody-11108762.html
