LY9 Antibody
Product Sizes
50 ul
£186.00
CSB-PA884511ESR2HU-50UL
100 ul
£334.00
CSB-PA884511ESR2HU-100UL
About this Product
- SKU:
- CSB-PA884511ESR2HU
- Additional Names:
- CD229 antibody; Cell surface molecule Ly-9 antibody; Cell surface molecule Ly9 antibody; hly9 antibody; LY 9 antibody; Ly9 antibody; LY9_HUMAN antibody; Lymphocyte antigen 9 antibody; mLY9 antibody; Signaling lymphocytic activation molecule 3 antibody; SLAM family member 3 antibody; SLAMF3 antibody; T lymphocyte surface antigen Ly9 precursor antibody; T-lymphocyte surface antigen Ly-9 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion; the costimulatory activity requires SH2D1A (PubMed:22184727). Promotes recruitment of RORC to the IL-17 promoter (PubMed:22989874). May be involved in the maintenance of peripheral cell tolerance by serving as a negative regulator of the immune response. May disable autoantibody responses and inhibit IFN-gamma secretion by CD4(+) T-cells. May negatively regulate the size of thymic innate CD8(+) T-cells and the development of invariant natural killer T (iNKT) cells (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human T-lymphocyte surface antigen Ly-9 protein (160-360AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:LY9-Antibody-11909837.html
