DKK4 Antibody

Product Sizes

50 ul

£186.00

CSB-PA883367ESR2HU-50UL

100 ul

£334.00

CSB-PA883367ESR2HU-100UL

About this Product

SKU:: CSB-PA883367ESR2HU
Additional Names:: Dickkopf 4 antibody; Dickkopf gene 4 antibody; Dickkopf homolog 4 (Xenopus laevis) antibody; Dickkopf homolog 4 antibody; Dickkopf related protein 4 antibody; Dickkopf-4 antibody; Dickkopf-related protein 4 short form antibody; Dickkopf4 antibody; DKK 4 antibody; Dkk-4 antibody; DKK4 antibody; DKK4_HUMAN antibody; hDkk 4 antibody; hDkk-4 antibody; hDkk4 antibody; MGC129562 antibody; MGC129563 antibody
Application:: ELISA, Immunohistochemistry, Western Blot
Buffer:: PBS
Clonality:: Polyclonal
Extra Details:: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Host:: Rabbit
Immunogen:: Recombinant Human Dickkopf-related protein 4 protein (19-224AA)
Isotype:: IgG
Physical State:: Liquid
Purification:: Affinity Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:: Cusabio
Type:: Antibody: Polyclonal Antibody

Basket