DKK4 Antibody
Product Sizes
50 ul
£186.00
CSB-PA883367ESR1HU-50UL
100 ul
£334.00
CSB-PA883367ESR1HU-100UL
About this Product
- SKU:
- CSB-PA883367ESR1HU
- Additional Names:
- Dickkopf 4 antibody; Dickkopf gene 4 antibody; Dickkopf homolog 4 (Xenopus laevis) antibody; Dickkopf homolog 4 antibody; Dickkopf related protein 4 antibody; Dickkopf-4 antibody; Dickkopf-related protein 4 short form antibody; Dickkopf4 antibody; DKK 4 antibody; Dkk-4 antibody; DKK4 antibody; DKK4_HUMAN antibody; hDkk 4 antibody; hDkk-4 antibody; hDkk4 antibody; MGC129562 antibody; MGC129563 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Dickkopf-related protein 4 protein (19-224AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DKK4-Antibody-11082376.html
