NOD2 Antibody
Product Sizes
50 ug
£186.00
CSB-PA881021LA01HU-50UG
100 ug
£334.00
CSB-PA881021LA01HU-100UG
About this Product
- SKU:
- CSB-PA881021LA01HU
- Additional Names:
- ACUG antibody; Arthrocutaneouveal granulomatosis antibody; BLAU antibody; CARD15 antibody; Caspase recruitment domain family, member 15 antibody; Caspase recruitment domain protein 15 antibody; Caspase recruitment domain-containing protein 15 antibody; CD antibody; CLR16.3 antibody; IBD1 antibody; Inflammatory bowel disease protein 1 antibody; LRR containing protein antibody; NLR family, CARD domain containing 2 antibody; NLRC2 antibody; NOD like receptor C2 antibody; NOD2 antibody; NOD2 protein antibody; NOD2_HUMAN antibody; NOD2B antibody; nucleotide binding oligomerization domain 2 antibody; Nucleotide binding oligomerization domain containing 2 antibody; Nucleotide binding oligomerization domain, leucine rich repeat and CARD domain containing 2 antibody; Nucleotide-binding oligomerization domain-containing protein 2 antibody; PSORAS1 antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Nucleotide-binding oligomerization domain-containing protein 2 protein (460-733AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NOD2-Antibody-12552929.html
