COPS7A Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA880068HC01HU-50UG
100 ug
£334.00
CSB-PA880068HC01HU-100UG
About this Product
- SKU:
- CSB-PA880068HC01HU
- Additional Names:
- COP9 complex subunit 7a antibody; COP9 constitutive photomorphogenic homolog subunit 7A antibody; COP9 signalosome complex subunit 7a antibody; COP9 signalosome subunit 7A antibody; COPS7A antibody; CSN7A antibody; CSN7A_HUMAN antibody; Dermal papilla derived protein 10 antibody; Dermal papilla-derived protein 10 antibody; DERP10 antibody; JAB1 containing signalosome subunit 7a antibody; JAB1-containing signalosome subunit 7a antibody; SGN7a antibody; Signalosome subunit 7a antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human COP9 signalosome complex subunit 7a protein (2-275AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:COPS7A-AntibodyFITC-conjugated-1090865.html
