GLRX2 Antibody
Product Sizes
50 ul
£186.00
CSB-PA878876DSR1HU-50UL
100 ul
£334.00
CSB-PA878876DSR1HU-100UL
About this Product
- SKU:
- CSB-PA878876DSR1HU
- Additional Names:
- bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2) antibody; bA101E13.1 antibody; CGI133 antibody; Glrx2 antibody; GLRX2_HUMAN antibody; Glutaredoxin-2 antibody; Glutaredoxin-2; mitochondrial antibody; GRX2 antibody; mitochondrial antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Glutaredoxin-2, mitochondrial protein (1-124AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GLRX2-Antibody-1091867.html
