RPRD1B Antibody, Biotin conjugated
Product Sizes
50 ug
£186.00
CSB-PA878854HD01HU-50UG
100 ug
£334.00
CSB-PA878854HD01HU-100UG
About this Product
- SKU:
- CSB-PA878854HD01HU
- Additional Names:
- RPRD1B antibody; C20orf77 antibody; CREPT antibody; Regulation of nuclear pre-mRNA domain-containing protein 1B antibody; Cell cycle-related and expression-elevated protein in tumor antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Regulation of nuclear pre-mRNA domain-containing protein 1B protein (2-172AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:RPRD1B-AntibodyBiotin-conjugated-11108737.html
