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Antibodies

TOLLIP Antibody, HRP conjugated

Product Sizes
50 ug
£186.00
CSB-PA875640LB01HU-50UG
100 ug
£334.00
CSB-PA875640LB01HU-100UG
About this Product
SKU:
CSB-PA875640LB01HU
Additional Names:
Adapter protein antibody; FLJ33531 antibody; IL 1RAcPIP antibody; IL1RAcPIP antibody; TOLIP antibody; TOLIP_HUMAN antibody; Toll interacting protein antibody; Toll-interacting protein antibody; tollip antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
HRP
Extra Details:
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Host:
Rabbit
Immunogen:
Recombinant Human Toll-interacting protein (86-163AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody