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Antibodies

ROS1 Antibody, Biotin conjugated

Product Sizes
50 ug
£186.00
CSB-PA874445LD01DOA-50UG
100 ug
£334.00
CSB-PA874445LD01DOA-100UG
About this Product
SKU:
CSB-PA874445LD01DOA
Additional Names:
ROS1 antibody; DML1 antibody; At2g36490 antibody; F1O11.12 antibody; DNA glycosylase/AP lyase ROS1 antibody; EC 4.2.99.18 antibody; DEMETER-like protein 1 antibody; Protein REPRESSOR OF SILENCING 1 antibody; Protein ROS1 antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Conjugate:
Biotin
Extra Details:
Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767). Generates 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464). Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752).
Host:
Rabbit
Immunogen:
Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Plant
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody