CNOT8 Antibody
Product Sizes
50 ul
£186.00
CSB-PA871398ESR2HU-50UL
100 ul
£334.00
CSB-PA871398ESR2HU-100UL
About this Product
- SKU:
- CSB-PA871398ESR2HU
- Additional Names:
- CAF 1 antibody; CAF 2 antibody; CAF1 antibody; CAF1 like protein antibody; CAF1-like protein antibody; CAF2 antibody; CALIF antibody; CALIFp antibody; CCR4 associated factor 8 antibody; CCR4 NOT transcription complex subunit 8 antibody; CCR4-associated factor 8 antibody; CCR4-NOT transcription complex subunit 8 antibody; CNOT 8 antibody; Cnot8 antibody; CNOT8_HUMAN antibody; hCAF1 antibody; PGK promoter directed over production antibody; POP 2 antibody; POP2 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CCR4-NOT transcription complex subunit 8 protein (1-292AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CNOT8-Antibody-1091208.html
