CHP2 Antibody
Product Sizes
100 ul
£332.00
CSB-PA869859-100UL
About this Product
- SKU:
- CSB-PA869859
- Additional Names:
- CHP2 antibody; HCA520Calcineurin B homologous protein 2 antibody; Hepatocellular carcinoma-associated antigen 520 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. Loftus B.J., Genomics 60:295-308(1999). Wang Y., J. Immunol. 169:1102-1109(2002). Pang T., J. Biol. Chem. 277:43771-43777(2002).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of HumanCHP2.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CHP2-Antibody-11085708.html
