SRGAP3 Antibody
Product Sizes
50 ul
£186.00
CSB-PA869737-50UL
100 ul
£334.00
CSB-PA869737-100UL
About this Product
- SKU:
- CSB-PA869737
- Additional Names:
- ARHGAP 14 antibody; ARHGAP14 antibody; Gbi antibody; ME GAP antibody; MEGAP antibody; Mental disorder associated GAP antibody; Mental disorder-associated GAP antibody; Rho GTPase activating protein 14 antibody; Rho GTPase-activating protein 14 antibody; SLIT ROBO Rho GTPase activating protein 3 antibody; SLIT-ROBO Rho GTPase-activating protein 3 antibody; srGAP 2 antibody; srGAP 3 antibody; srGAP2 antibody; srGAP3 antibody; SRGP 2 antibody; SRGP2 antibody; SRGP3_HUMAN antibody; WAVE associated Rac GTPase activating protein antibody; WAVE-associated Rac GTPase-activating protein antibody; WRP antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- SRGAP3 is a 1099 amino acid protein containing 1 FCH domain, 1 Rho-GAP domain and 1 SH3 domain. Expressed highly in brain, and in lower levels in kidney, WRP is thought to play a role in cell migration through its interaction with Cdc42 and Rac1. Cdc42 and Rac1 are two intracellular signaling proteins that regulate the multistep cell migration process. WRP downregulates Cdc42 and Rac1 activity, thereby impairing actin and microtubule dynamics, the formation of protrusions, and total cell migration. Defects in the gene encoding WRP have been linked to severe idiopathic mental retardation. Three isoforms of WRP exist as a result of alternative splicing events.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human SRGAP3
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:SRGAP3-Antibody-11102194.html
