IDE Antibody
Product Sizes
50 ul
£186.00
CSB-PA869336-50UL
100 ul
£334.00
CSB-PA869336-100UL
About this Product
- SKU:
- CSB-PA869336
- Additional Names:
- Abeta-degrading protease antibody; FLJ35968 antibody; Ide antibody; IDE_HUMAN antibody; Insulin protease antibody; Insulin-degrading enzyme antibody; Insulinase antibody; Insulysin antibody; OTTHUMP00000020097 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human IDE
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:IDE-Antibody-11099589.html
