NMRAL1 Antibody, Biotin conjugated
Product Sizes
50 ug
£186.00
CSB-PA867194LD01HU-50UG
100 ug
£334.00
CSB-PA867194LD01HU-100UG
About this Product
- SKU:
- CSB-PA867194LD01HU
- Additional Names:
- FLJ25918 antibody; HSCARG antibody; NmrA like family domain containing 1 antibody; NmrA like family domain containing protein 1 antibody; NmrA-like family domain-containing protein 1 antibody; NMRAL1 antibody; NMRL1_HUMAN antibody; SDR48A1 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human NmrA-like family domain-containing protein 1 protein (1-299AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NMRAL1-AntibodyBiotin-conjugated-11110164.html
