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Antibodies

IFT57 Antibody

Product Sizes
50 ul
£186.00
CSB-PA865156ESR2HU-50UL
100 ul
£334.00
CSB-PA865156ESR2HU-100UL
About this Product
SKU:
CSB-PA865156ESR2HU
Additional Names:
CDNA FLJ10147 fis clone HEMBA1003369 antibody; Dermal papilla derived protein 8 antibody; Dermal papilla-derived protein 8 antibody; DERP 8 antibody; DERP8 antibody; Esrrbl 1 antibody; Esrrbl1 antibody; ESRRBL1 protein antibody; Estrogen related receptor beta like 1 antibody; Estrogen related receptor beta like protein 1 antibody; Estrogen-related receptor beta-like protein 1 antibody; FLJ10147 antibody; Hip1 Interacting protein antibody; HIP1 interacting protein HIPPI antibody; Hip1 protein interactor antibody; HIP1-interacting protein antibody; HIPPI antibody; Huntingtin interacting protein 1 interacting protein antibody; Huntingtin interacting protein 1 protein interactor antibody; IFT 57 antibody; ift57 antibody; IFT57_HUMAN antibody; Intraflagellar transport 57 homolog (Chlamydomonas) antibody; Intraflagellar transport 57 homolog antibody; Intraflagellar transport protein 57 homolog antibody; MHS4R2 antibody; Vestrogen related receptor beta like 1 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Host:
Rabbit
Immunogen:
Recombinant Human Intraflagellar transport protein 57 homolog protein (170-429AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody