PIF1 Antibody
Product Sizes
50 ug
£186.00
CSB-PA863987LA01HU-50UG
100 ug
£334.00
CSB-PA863987LA01HU-100UG
About this Product
- SKU:
- CSB-PA863987LA01HU
- Additional Names:
- ATP dependent DNA helicase PIF1 antibody; ATP-dependent DNA helicase PIF1 antibody; C15orf20 antibody; DNA helicase homolog PIF1 antibody; DNA helicase PIF1 antibody; DNA repair and recombination helicase PIF1 antibody; Petite integration frequency 1 antibody; PIF antibody; PIF1 5' to 3' DNA helicase antibody; PIF1 5' to 3' DNA helicase homolog antibody; PIF1 antibody; PIF1 DNA helicase antibody; PIF1/RRM3 DNA helicase like protein antibody; PIF1/RRM3 DNA helicase-like protein antibody; PIF1_HUMAN antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ATP-dependent DNA helicase PIF1 protein (125-360AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PIF1-Antibody-12259068.html
