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Antibodies

CPEB1 Antibody, FITC conjugated

Product Sizes
50 ug
£186.00
CSB-PA861184LC01HU-50UG
100 ug
£334.00
CSB-PA861184LC01HU-100UG
About this Product
SKU:
CSB-PA861184LC01HU
Additional Names:
CEBP antibody; CPE binding protein 1 antibody; CPE BP1 antibody; CPE-binding protein 1 antibody; CPE-BP1 antibody; CPEB 1 antibody; CPEB antibody; CPEB-1 antibody; CPEB1 antibody; CPEB1 protein antibody; CPEB1_HUMAN antibody; Cytoplasmic polyadenylation binding protein 1 antibody; Cytoplasmic polyadenylation element binding protein antibody; Cytoplasmic polyadenylation element binding protein 1 antibody; Cytoplasmic polyadenylation element-binding protein 1 antibody; FLJ13203 antibody; h CEBP antibody; h-CEBP antibody; hCPEB 1 antibody; hCPEB-1 antibody; MGC34136 antibody; MGC60106 antibody; mKIAA0940 antibody; MKIAA0940 protein antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
FITC
Extra Details:
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
Host:
Rabbit
Immunogen:
Recombinant Human Cytoplasmic polyadenylation element-binding protein 1 protein (1-486AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody