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Antibodies

AIM2 Antibody

Product Sizes
50 ul
£186.00
CSB-PA858560-50UL
100 ul
£334.00
CSB-PA858560-100UL
About this Product
SKU:
CSB-PA858560
Additional Names:
Absent in melanoma 2 antibody; AIM 2 antibody; Aim2 antibody; AIM2_HUMAN antibody; Interferon-inducible protein AIM2 antibody; OTTHUMP00000035296 antibody; PYHIN4 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN- , AIM2 is thought to act as a tumor suppressor by repressing NF B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
Host:
Rabbit
Immunogen:
Fusion protein of Human AIM2
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA858560(AIM2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA858560(AIM2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200)