RBBP8 Antibody
Product Sizes
50 ug
£186.00
CSB-PA857871LA01HU-50UG
100 ug
£334.00
CSB-PA857871LA01HU-100UG
About this Product
- SKU:
- CSB-PA857871LA01HU
- Additional Names:
- COM1 antibody; COM1_HUMAN antibody; CtBP interacting protein antibody; CtBP-interacting protein antibody; CtIP antibody; DNA endonuclease RBBP8 antibody; JWDS antibody; RB binding protein 8 endonuclease antibody; RBBP-8 antibody; RBBP8 antibody; Retinoblastoma-binding protein 8 antibody; Retinoblastoma-interacting protein and myosin-like antibody; Rim antibody; SAE2 antibody; SCKL2 antibody; Sporulation in the absence of SPO11 protein 2 homolog antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA endonuclease RBBP8 protein (126-331AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:RBBP8-Antibody-12548714.html
