RAD9A Antibody, HRP conjugated
Product Sizes
50 ug
£186.00
CSB-PA857455LB01HU-50UG
100 ug
£334.00
CSB-PA857455LB01HU-100UG
About this Product
- SKU:
- CSB-PA857455LB01HU
- Additional Names:
- Cell cycle checkpoint control protein antibody; Cell cycle checkpoint control protein RAD9A antibody; DNA repair exonuclease rad9 homolog A antibody; hRAD 9 antibody; hRAD9 antibody; Rad 9 antibody; RAD 9A antibody; RAD9 (S pombe) homolog antibody; RAD9 homolog A antibody; RAD9 homolog antibody; Rad9a antibody; RAD9A_HUMAN antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Extra Details:
- Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cell cycle checkpoint control protein RAD9A protein (267-341AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:RAD9A-AntibodyHRP-conjugated-12556458.html
