MYLIP Antibody
Product Sizes
50 ul
£186.00
CSB-PA855506ESR2HU-50UL
100 ul
£334.00
CSB-PA855506ESR2HU-100UL
About this Product
- SKU:
- CSB-PA855506ESR2HU
- Additional Names:
- BM-023 antibody; BZF1 antibody; E3 ubiquitin protein ligase MYLIP antibody; E3 ubiquitin-protein ligase MYLIP antibody; Idol antibody; Inducible degrader of the LDL-receptor antibody; Lipoprotein receptor antibody; MIR antibody; MYLIP antibody; MYLIP_HUMAN antibody; Myosin regulatory light chain interacting protein antibody; PP5242 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MYLIP-Antibody-11909584.html
