FCRL3 Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA853475LC01HU-50UG
100 ug
£334.00
CSB-PA853475LC01HU-100UG
About this Product
- SKU:
- CSB-PA853475LC01HU
- Additional Names:
- CD307c antibody; Fc receptor homolog 3 antibody; Fc receptor-like protein 3 antibody; FcR-like protein 3 antibody; FcRH3 antibody; FcRL3 antibody; FCRL3_HUMAN antibody; hIFGP3 antibody; IFGP family protein 3 antibody; IFGP3 antibody; Immune receptor translocation-associated protein 3 antibody; Immunoglobulin superfamily receptor translocation associated protein 3 antibody; IRTA3 antibody; SH2 domain-containing phosphatase anchor protein 2 antibody; SPAP2 antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Fc receptor-like protein 3 protein (122-222AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:FCRL3-Antibody--FITC-conjugated-12921959.html
