PIEZO1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA852881ESR1HU-50UL
100 ul
£334.00
CSB-PA852881ESR1HU-100UL
About this Product
- SKU:
- CSB-PA852881ESR1HU
- Additional Names:
- DHS antibody; Fam38a antibody; Family with sequence similarity 38 member A antibody; KIAA0233 antibody; Membrane protein induced by beta-amyloid treatment antibody; Mib antibody; PIEZ1_HUMAN antibody; Piezo-type mechanosensitive ion channel component 1 antibody; PIEZO1 antibody; Protein FAM38A antibody; Protein FAM38B antibody; Protein PIEZO1 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Pore-forming subunit of a mechanosensitive non-specific cation channel (PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling (PubMed:20016066). In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation (PubMed:25119035). Plays a key role in blood vessel formation and vascular structure in both development and adult physiology (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Piezo-type mechanosensitive ion channel component 1 protein (2230-2420AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PIEZO1-Antibody-11909808.html
