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Antibodies

MICAL1 Antibody, HRP conjugated

Product Sizes
50 ul
£186.00
CSB-PA851555LB01HU-50UL
100 ul
£334.00
CSB-PA851555LB01HU-100UL
About this Product
SKU:
CSB-PA851555LB01HU
Additional Names:
CasL interacting molecule antibody; DKFZp434B1517 antibody; FLJ11937 antibody; FLJ21739 antibody; MICA1_HUMAN antibody; MICAL 1 antibody; MICAL antibody; MICAL1 antibody; microtubule associated monoxygenase; calponin and LIM domain containing 1 antibody; Molecule interacting with CasL protein 1 antibody; NEDD9 interacting protein with calponin homology and LIM domains antibody; NEDD9-interacting protein with calponin homology and LIM domains antibody; NICAL antibody; OTTHUMP00000016969 antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Conjugate:
HRP
Extra Details:
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4. Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections. Through redox regulation of the actin cytoskeleton controls the intracellular distribution of sectrory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels (By similarity). May act as Rab effector protein and play a role in vesicle trafficking.
Host:
Rabbit
Immunogen:
Recombinant Human [F-actin]-methionine sulfoxide oxidase MICAL1 protein (806-1067AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody