CHCHD4 Antibody
Product Sizes
50 ug
£186.00
CSB-PA850802HA01HU-50UG
100 ug
£334.00
CSB-PA850802HA01HU-100UG
About this Product
- SKU:
- CSB-PA850802HA01HU
- Additional Names:
- CHCHD4 antibody; MIA40Mitochondrial intermembrane space import and assembly protein 40 antibody; Coiled-coil-helix-coiled-coil-helix domain-containing protein 4 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Mitochondrial intermembrane space import and assembly protein 40 protein (1-142AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CHCHD4-Antibody-1090274.html
