CIART Antibody, Biotin conjugated
Product Sizes
50 ug
£186.00
CSB-PA850790LD01HU-50UG
100 ug
£334.00
CSB-PA850790LD01HU-100UG
About this Product
- SKU:
- CSB-PA850790LD01HU
- Additional Names:
- CIART antibody; C1orf51Circadian-associated transcriptional repressor antibody; ChIP-derived repressor of network oscillator antibody; Chrono antibody; Computationally highlighted repressor of the network oscillator antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. Rhythmically binds the E-box elements (5'-CACGTG-3') on circadian gene promoters and its occupancy shows circadian oscillation antiphasic to ARNTL/BMAL1. Interacts with the glucocorticoid receptor (NR3C1) and contributes to the repressive function in the glucocorticoid response (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Circadian-associated transcriptional repressor protein (1-385AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CIART-AntibodyBiotin-conjugated-11106963.html
