NEIL1 Antibody
Product Sizes
50 ug
£186.00
CSB-PA846619LA01HU-50UG
100 ug
£334.00
CSB-PA846619LA01HU-100UG
About this Product
- SKU:
- CSB-PA846619LA01HU
- Additional Names:
- DNA (apurinic or apyrimidinic site) lyase Neil1 antibody; DNA glycosylase/AP lyase Neil 1 antibody; DNA glycosylase/AP lyase Neil1 antibody; DNA-(apurinic or apyrimidinic site) lyase Neil1 antibody; Endonuclease 8 like 1 antibody; Endonuclease 8-like 1 antibody; Endonuclease VIII antibody; Endonuclease VIII like 1 antibody; Endonuclease VIII-like 1 antibody; FLJ22402 antibody; FPG1 antibody; hFPG1 antibody; NEH 1 antibody; NEH1 antibody; NEI 1 antibody; Nei endonuclease VIII like 1 (E. coli) antibody; Nei endonuclease VIII like 1 antibody; Nei homolog 1 antibody; Nei like 1 antibody; Nei like protein 1 antibody; Nei-like protein 1 antibody; NEI1 antibody; NEIL 1 antibody; Neil1 antibody; NEIL1_HUMAN antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Endonuclease 8-like 1 protein (2-390AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NEIL1-Antibody-1029463.html
