MAML1 Antibody, HRP conjugated
Product Sizes
50 ug
£186.00
CSB-PA838784LB01HU-50UG
100 ug
£334.00
CSB-PA838784LB01HU-100UG
About this Product
- SKU:
- CSB-PA838784LB01HU
- Additional Names:
- Mam-1 antibody; Mam1 antibody; MAML 1 antibody; Maml1 antibody; MAML1_HUMAN antibody; Mastermind like 1 antibody; Mastermind-like protein 1 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Extra Details:
- Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Mastermind-like protein 1 protein (1-45AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MAML1-AntibodyHRP-conjugated-12258693.html
