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Antibodies

DOCK7 Antibody, FITC conjugated

Product Sizes
50 ug
£186.00
CSB-PA836266LC01HU-50UG
100 ug
£334.00
CSB-PA836266LC01HU-100UG
About this Product
SKU:
CSB-PA836266LC01HU
Additional Names:
DOCK7 antibody; KIAA1771Dedicator of cytokinesis protein 7 antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
FITC
Extra Details:
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody