DPF1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA835697ESR1HU-50UL
100 ul
£334.00
CSB-PA835697ESR1HU-100UL
About this Product
- SKU:
- CSB-PA835697ESR1HU
- Additional Names:
- BAF45B antibody; BRG1-associated factor 45B antibody; D4 antibody; D4 zinc and double PHD fingers family 1 antibody; DPF1 antibody; DPF1_HUMAN antibody; NEUD4 antibody; Neuro d4 homolog antibody; Zinc and double PHD fingers family 1 antibody; Zinc finger protein neuro-d4 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Zinc finger protein neuro-d4 protein (261-380AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DPF1-Antibody-11909061.html
