CXADR Antibody
Product Sizes
100 ul
£332.00
CSB-PA830526-100UL
About this Product
- SKU:
- CSB-PA830526
- Additional Names:
- 46 kD coxsackievirus and adenovirus receptor CAR protein antibody; 46 kD coxsackievirus and adenovirus receptor protein antibody; CAR antibody; CAR4/6 antibody; Coxsackie virus and adenovirus receptor antibody; Coxsackie virus B receptor antibody; Coxsackievirus and adenovirus receptor antibody; Coxsackievirus B adenovirus receptor antibody; Coxsackievirus B-adenovirus receptor antibody; CVB3 binding protein antibody; CVB3-binding protein antibody; Cxadr antibody; CXADR Ig like cell adhesion molecule antibody; CXAR_HUMAN antibody; hCAR antibody; HCVADR antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. Tomko R.P., Proc. Natl. Acad. Sci. U.S.A. 94:3352-3356(1997). Bergelson J.M., Science 275:1320-1323(1997). Bowles K.R., Hum. Genet. 105:354-359(1999).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human CXADR.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CXADR-Antibody-11085824.html
