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Antibodies

ERCC1 Antibody

Product Sizes
100 ul
£332.00
CSB-PA827559-100UL
About this Product
SKU:
CSB-PA827559
Additional Names:
COFS 4 antibody; COFS4 antibody; DNA excision repair protein ERCC 1 antibody; DNA excision repair protein ERCC-1 antibody; DNA excision repair protein ERCC1 antibody; ERCC 1 antibody; ERCC1 antibody; ERCC1_HUMAN antibody; Excision repair cross complementation group 1 antibody; Excision repair cross complementing 1 antibody; Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody; Excision repair protein antibody; RAD 10 antibody; RAD10 antibody; UV 20 antibody; UV20 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. Kan-Tai Hsia, Development, Jan 2003; 130: 369. Jim Selfridge, Nucleic Acids Res., Nov 2001; 29: 4541 - 4550. Cha-Kyung Youn, Cancer Res., Jul 2004; 64: 4849 - 4857. Teresa A. Motycka, J. Biol. Chem., Apr 2004; 279: 13634 - 13639.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from Human ERCC1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody