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Antibodies

EPOR (Ab-426) Antibody

Product Sizes
100 ul
£332.00
CSB-PA826447-100UL
About this Product
SKU:
CSB-PA826447
Additional Names:
EPO R antibody; EPO Receptor antibody; EPO-R antibody; epor antibody; EPOR_HUMAN antibody; Erythropoietin receptor antibody; Erythropoietin receptor precursor antibody; MGC138358 antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling. Winkelmann J.C., Blood 76:24-30(1990) [PubMed: 2163695]. Jones S.S.,Blood 76:31-35(1990) [PubMed: 2163696]. Noguchi C.T., Blood 78:2548-2556(1991) [PubMed: 1668606].
Host:
Rabbit
Immunogen:
Synthesized peptide derived from Internal of Human Epo-R.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody