DKC1 Antibody
Product Sizes
100 ul
£332.00
CSB-PA820074-100UL
About this Product
- SKU:
- CSB-PA820074
- Additional Names:
- CBF5 antibody; CBF5 homolog antibody; Cbf5p homolog antibody; DKC 1 antibody; DKC antibody; Dkc1 antibody; DKC1_HUMAN antibody; DKCX antibody; Dyskeratosis congenita 1 antibody; Dyskeratosis congenita 1 dyskerin antibody; Dyskerin antibody; H/ACA ribonucleoprotein complex subunit 4 antibody; NAP 57 antibody; NAP57 antibody; NOLA 4 antibody; NOLA4 antibody; Nopp140 associated protein of 57 kDa antibody; Nopp140-associated protein of 57 kDa antibody; Nucleolar protein family A member 4 antibody; Nucleolar protein NAP57 antibody; snoRNP protein DKC1 antibody; XAP 101 antibody; XAP101 antibody
- Application:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Isoform 1:Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.Isoform 3:Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression (when overexpressed in HeLa cells). Heiss N.S., Nat. Genet. 19:32-38(1998). Knight S.W., Am. J. Hum. Genet. 65:50-58(1999). Hassock S., Genomics 55:21-27(1999).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Internal of Human Dyskerin.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DKC1-Antibody-11084784.html
